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The treatment of onchocerciasis with diethylcarbamazine and suramin is associated with an exacerbation of ocular disease. Here we show that, through its spacer domain, Drosophila PAR-1 accumulates on the lateral plasma membrane (PM) in cells of the follicular epithelium (FE).
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Structure and localization of mRNA encoding a pigment dispersing hormone (PDH) in the eyestalk of the crayfish Orconectes limosus. Biscarpamontamine B (2) showed potent cytotoxicity against various human cancer cell lines.
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